Grant Amount: Varies, Between $200,000 and $400,000 Additional Information -
Deadline: May 14, 2022 for all opportunities
Parkinson’s Pathway Biomarkers
Amount: $300,000
The goal of the program is to develop biomarkers that can support therapeutic development for priority pathways in Parkinson's Disease. Specifically it is aimed at (1) sensitive measurements of pathway activation/dysfunction and (2) improving technologies for analyzing the target/pathway of interest. MJFF considers priority pathways to include: mitochondrial function, lysosomal function, autophagy, inflammation, protein handling, protein trafficking, etc.
Link to Complete RFP
Target Advancement Program
Amount: $200,000
The Target Advancement Program seeks to build conclusive evidence to rationalize biological targets and pathways for Parkinson’s disease (PD) therapeutic development. Funding will support projects focused on validating targets and defining pathways implicated in PD pathological processes and/or symptomology. Targets and pathways proposed for study should have a reasonable initial link to PD, such as demonstrated genetic association, altered expression/function of the target in PD-relevant human tissue, and/or prior clinical trial data. When considering validation studies, MJFF prioritizes applications proposing experimental systems and models with high construct validity to hypothesized pathogenic mechanisms in human PD, such as patient-derived material and/or animal models demonstrating dysfunction in the pathway(s) proposed for study.
Link to Complete RFP
Investigating Environmental Factors that Increase the Risk for Parkinson’s Disease
Amount: $400,000
The Investigating Environmental Risk Factors that Increase the Risk for Parkinson’s Disease program supports the analysis of large epidemiological datasets to identify environmental risk factors, such as exposure to chemicals, toxic emissions, air pollutants, and dietary contaminants, which are associated with an increased risk of PD. MJFF is especially interested in funding projects that utilize large longitudinal datasets and will prioritize collaborative efforts that bring together teams of investigators with access to multiple diverse datasets. This program is not appropriate for studies that require additional or prospective data collection.
Link to Complete RFP
Please contact Lynn Wong if you are interested in applying to these opportunities.