If Mitochondria Don't Move, Motor Neuron Disease May Develop

Jan 01, 2014 12:00 AM

Author: Janet Shaw

Tags: Driving Discovery

Researchers long have known of a connection between mitochondrial function and distribution and neural disease, but they hadn’t been able to tell whether a defect occurs because mitochondria isn’t functioning properly or isn’t getting to the right.

Biochemistry professor Janet Shaw, Ph.D., and M.D./Ph.D. student Tammy T. Nguyen led a study that addressed that question and found that when mitochondria weren’t distributed along the spinal cord and axons in mouse models they developed, the animals developed symptoms of neurodegenerative diseases.

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