Mouse Model Provides Window into the Working Brain

Jan 01, 2014 12:00 AM

Author: Peter Tvrdik

University of Utah scientists developed a genetically engineered line of mice that is expected to open the door to new research on epilepsy, Alzheimer's and other diseases.

The mice carry a protein marker, which changes in degree of fluorescence in response to different calcium levels. This will allow researchers to study many cell types, including astrocytes and microglia, in a new way. John White, Ph.D., professor of bioengineering and executive director of the Brain Institute, is corresponding author of the study. Peter Trvdik, Ph.D., a fellow in human genetics, is senior author, and J. Michael Gee, who is pursing and M.D. and graduate degree in bioengineering, is first author.

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