The most common type of breast cancer is estrogen receptor-positive (ER+). ER+ tumors can be successfully treated with hormone therapy, but many tumors acquire endocrine resistance which limits treatment options...
Models that recapitulate the complexity of human tumors are urgently needed to develop more effective cancer therapies. We report a bank of human patient-derived xenografts (PDXs) and matched organoid cultures...
December 2021: New work from Alana Welm’s lab reveals a novel immunotherapy target for metastatic breast cancer. A study published in Cancer Discovery shows that blocking short form Ron kinase...