close-up of slide

The Nuclear Control of Cell Growth and Differentiation (NC) Program aims to provide new understanding of the genetics and mechanics of cancer development. This program’s research focuses on the basic processes in the nucleus of cells that go awry in cancer and how they contribute to cancer’s development. The purpose is to identify optimal targets for translational research.

Within that broad goal, research in the NC program can be separated into three theme areas:

  • Understanding gene regulation mechanisms of importance in oncogenesis at transcriptional and post-transcriptional levels in normal and cancer cells, with focus on chromatin and epigenetics
  • Unraveling the interplay between metabolic derangements and transcription in cancer cells
  • Investigating the mechanisms that maintain genome stability and their impact on cancer

Program Membership

HCI Cancer Center members enjoy a variety of benefits, including eligibility for leadership roles in the Center, institutional funding opportunities, and scientific/administrative support.

News & Blog

Huntsman Cancer Institute’s Renovated ‘Beacon of Hope’ Will Light in Remembrance of Founder, Jon M. Huntsman
health-care-trans
Feb 01, 2019

Huntsman Cancer Institute’s Renovated ‘Beacon of Hope’ Will Light in Remembrance of Founder, Jon M. Huntsman

Huntsman Cancer Institute,

Jon M. Huntsman, Sr. was a visionary philanthropist who made it his personal mission to eradicate cancer from the face of the Earth. He often described his devastation after the loss of several family members and close friends to the disease. In the 1990s, he received his first of four cancer diagnoses. His personal experiences with cancer ignited a determination to make a difference. After he completed treatments, Huntsman and his family vowed to use their considerable means to transform the experience for cancer patients and to advance research. Vision began its course to reality with the founding a cancer center that would bear the Huntsman family name. ... Read More

Huntsman Cancer Institute’s Next Expansion for Cancer Patients Nearly Doubles in Size Thanks to a $30 Million Gift from the Huntsman Foundation
health-care-trans
Jan 11, 2019

Huntsman Cancer Institute’s Next Expansion for Cancer Patients Nearly Doubles in Size Thanks to a $30 Million Gift from the Huntsman Foundation

Huntsman Cancer Institute,

Peter Huntsman, CEO of the Huntsman Foundation and chairman and CEO of the Huntsman Cancer Foundation (HCF), announced today a transformational $30 million gift from the family’s foundation. This donation allows Huntsman Cancer Institute (HCI) at the University of Utah (U of U) to better plan for and address the future needs of cancer patients in the Mountain West. The gift is in addition to the $40 million already raised by HCF to support the construction of the Kathryn F. Kirk Center for Comprehensive Cancer Care and Women’s Cancers at Huntsman Cancer Institute. ... Read More

Huntsman Cancer Institute Helps Develop BRCA Exchange to Inform Understanding of Cancer Risk by Aggregating Data on Thousands of BRCA1 and BRCA2 Mutations
education
Jan 09, 2019

Huntsman Cancer Institute Helps Develop BRCA Exchange to Inform Understanding of Cancer Risk by Aggregating Data on Thousands of BRCA1 and BRCA2 Mutations

Huntsman Cancer Institute,

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) contributed to the development of a global resource that includes data on thousands of inherited variants in the BRCA1 and BRCA2 genes. This resource, called the BRCA Exchange, is now available to the public. The BRCA Exchange was created through the BRCA Challenge, a long-term demonstration project initiated by the Global Alliance for Genomics and Health (GA4GH) to enhance sharing of BRCA1/BRCA2 data. The new resource will allow clinicians to review expert classifications of variants in these major cancer predisposition genes as part of their individual assessment of cancer prevention, screenings, and interventions for patients at higher risk for breast, ovarian, and certain other cancers. ... Read More

Huntsman Cancer Institute Launches Innovative Service Providing Cancer Care at Home
clinical
Dec 13, 2018

Huntsman Cancer Institute Launches Innovative Service Providing Cancer Care at Home

Huntsman Cancer Institute,

Huntsman Cancer Institute (HCI) at the University of Utah (U of U) has launched a unique new service called Huntsman at Home. This service brings HCI-quality care into the homes of HCI patients, whose medical needs range from symptom management to physical therapy after cancer surgery to end-of-life care. Huntsman at Home may also allow patients to be discharged from the HCI cancer hospital sooner by enabling them to receive follow-up care in their own home. ... Read More

  Researchers Develop Personalized Medicine Tool for  Inherited Colorectal Cancer Syndrome Risk
health-care-trans
Dec 10, 2018

Researchers Develop Personalized Medicine Tool for Inherited Colorectal Cancer Syndrome Risk

Huntsman Cancer Institute,

An international team of researchers led by Huntsman Cancer Institute (HCI) at the University of Utah (U of U) has developed, calibrated, and validated a novel tool for identifying the genetic changes in Lynch syndrome genes that are likely to be responsible for causing symptoms of the disease. The results were published this week in the journal Genetics in Medicine. ... Read More