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The Nuclear Control of Cell Growth and Differentiation (NC) Program aims to provide new understanding of the genetics and mechanics of cancer development. This program’s research focuses on the basic processes in the nucleus of cells that go awry in cancer and how they contribute to cancer’s development. The purpose is to identify optimal targets for translational research.

Within that broad goal, research in the NC program can be separated into three theme areas:

  • Understanding gene regulation mechanisms of importance in oncogenesis at transcriptional and post-transcriptional levels in normal and cancer cells, with focus on chromatin and epigenetics
  • Unraveling the interplay between metabolic derangements and transcription in cancer cells
  • Investigating the mechanisms that maintain genome stability and their impact on cancer

Program Membership

HCI Cancer Center members enjoy a variety of benefits, including eligibility for leadership roles in the Center, institutional funding opportunities, and scientific/administrative support.

News Highlights from the Nuclear Control Program

Together We Care Compassionately
Mar 01, 2019

Together We Care Compassionately

Approximately 500 patients visit the outpatient clinics and infusion center at Huntsman Cancer Institute each day. Our patients rely on our clinical teams and staff to provide safe, efficient, and high quality care during each clinic visit. In this letter from Don Milligan, director of outpatient services, highlights recent efforts to provide the best care possible.... Read More

A Bad Influence: The Interplay between Tumor Cells and Immune Cells
Oct 16, 2018

A Bad Influence: The Interplay between Tumor Cells and Immune Cells

Research at Huntsman Cancer Institute at the University of Utah yielded new insights into the environment surrounding different types of lung tumors, and described how these complex cell ecosystems may in turn ultimately affect response to treatment. The results were published today in Immunity and featured on the print cover of the journal. ... Read More

Talks with Docs: Cindy Matsen, MD
Oct 04, 2018

Talks with Docs: Cindy Matsen, MD

At Huntsman Cancer Institute, Dr. Cindy Matsen helps provide patients with surgical options as they undergo treatment for their breast cancer. In this interview, we learn about the relationships she builds with her female patients and what they teach her every day. ... Read More

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