The Cell Response and Regulation (CRR) Program works to decipher cellular mechanisms of cancer biology, through transdisciplinary research, providing a foundation for new approaches to clinical issues.
The program’s research focuses on the mechanisms by which cancer cells become transformed and/or progress to the metastatic malignant state.
CRR research is centered around the following three Specific Aims:
- To understand cellular mechanisms underlying tumor development
- To uncover mechanisms and pathways mediating tumor evolution and metastasis
- To elucidate the complex interactions among tumor cells, immune cells, and their microenvironment