High Throughput Genomics

The High Throughput Genomics Shared Resource provides experimental support for diverse genomic applications that utilize the Illumina sequencing platform. The Resource operates as a full-service facility that offers expertise in all aspects of the experimental process including evaluation of sample quality, construction of Illumina sequencing libraries (genomic DNA, exome and targeted enrichment, methylation analysis, ChIP-seq, RNA-Seq, Small RNA-Seq, ribosome profiling, and single cell analysis), qualifying and normalizing libraries and sequencing on an Illumina instrument.

Key instrumentation within the 1800 ft2 laboratory includes an Illumina NovaSeq 6000, two Illumina HiSeq 2500 instruments, two MiSeq instruments, a 10X Genomics Chromium Controller, a Fluidigm C1 Single-Cell AutoPrep System, an Agilent 2200 TapeStation, a Covaris E210 and an S2 Focussed-Ultrasonnicator, and a Bio-Rad CFX Connect Real Time System. A database and LIMS system, GNomEx, has been designed and implemented to track and store experimental information and enable data distribution.

Services

  • Sample Quality Assays
  • Library Preparation
  • Library Quality Control
  • Illumina Sequencing

Location

High Throughput Genomics Shared Resource
Huntsman Cancer Institute Room 1753
2000 Circle of Hope
University of Utah
Salt Lake City UT 84112

Contact Us

High Throughput Genomics Director
Brian K. Dalley, PhD
brian.dalley@hci.utah.edu
801-585-7192

Governance

HCI Senior Director Oversight
Bradley Cairns, PhD

Faculty Advisory Committee Chair
Katherine Varley, PhD

Faculty Advisory Committee Members
Richard Clark, PhD
Jason Gertz, PhD
Christopher Gregg, PhD
Mei Koh, PhD
Philip Moos, PhD
Andrew Post, MD, PhD
Sean Tavtigian, PhD
Joseph Yost, PhD