Cardiovascular Bridge
Paul Bray, MD
Title: Professor - Internal Medicine (Hematology/BMT)
Dr. Bray’s laboratory studies the role of platelets in cardiovascular
3i Bridge/Pillar: Cardiovascular
Keywords: transcriptomics, functional genomics, platelets, megakaryocytopoiesis, microRNAs
Email: paul.bray@hsc.utah.edu
Robert Campbell, PhD
Title: Research Assistant Professor - Internal Medicine (General Internal Medicine)
The primary goal of Dr. Campbell’s research is to determine how blood clots induce robust transcriptional and translational responses in immune cells, which promotes inflammation and thrombosis. During my training, I have focused on dissecting the mechanisms behind how cells alter coagulation under normal and disease situations. Recently, I have begun to examine how hemostasis and thrombosis
3i Bridge/Pillar: Cardiovascular
Keywords: thrombosis, platelets, infection, inflammation, aging
Email: rcampbell@u2m2.utah.edu
Tony Donato, PhD
Title: Associate Professor - Internal Medicine (Geriatrics)
The primary research direction in the Translational Vascular Physiology lab is determining how arteries develop inflammation and oxidative stress with aging and increase our risk of developing vascular diseases. Another recent focus is understanding the vascular etiology of a two of rare diseases, systemic sclerosis (SSC) and cerebral cavernous malformations (CCM), and providing
3i Bridge/Pillar: Cardiovascular
Keywords: arteries, endothelium, inflammation, oxidative stress, Aging, rare diseases
Email: tony.donato@hsc.utah.edu
Jim Fang, MD
Title: Professor - Internal Medicine (Cardiovascular Medicine)
My interests include the pathophysiology of heart failure with preserved ejection fraction as well as heart failure with recovered ejection fraction.
3i Bridge/Pillar: Cardiovascular
Keywords: heart failure, diastolic heart failure, myocardial recovery
Email: james.fang@hsc.utah.edu
Lisa Lesniewski, PhD
Title: Associate Professor - Internal Medicine (Geriatrics)
My laboratory explores mechanisms underlying age- and obesity-associated vascular and metabolic dysfunction and disease. Using genetic, pharmacologic and surgical approaches, we explore the role of
3i Bridge/Pillar: Cardiovascular
Keywords: aging, obesity, atherosclerosis, insulin sensitivity, glucose tolerance, endothelium
Email: Lisa.Lesniewski@utah.edu
Scott McNally, MD, PhD
Title: Assistant Professor - Radiology and Imaging Sciences
Our group’s scientific mission is to optimally detect vascular disease using advanced imaging techniques, with the overall aim to improve diagnosis and treatment of cerebrovascular disease.
3i Bridge/Pillar: Cardiovascular
Keywords: magnetic resonance imaging, stroke, blood vessels, atherosclerosis, inflammation, oxidative stress
Email: Scott.Mcnally@hsc.utah.edu
Matt Rondina, MD
Title: Associate Professor - Internal Medicine (General Internal Medicine)
Our research program focuses on platelet and megakaryocyte gene expression and function during thrombo-inflammatory syndromes. To answer clinically-relevant questions, we utilize primary human cells and samples from patients as well as relevant experimental model systems. Current projects in the lab span from studies in patients with infectious diseases (e.g. sepsis, dengue, influenza) to aging and cardiometabolic disorders.
3i Bridge/Pillar: Cardiovascular
Keywords: platelets, sepsis, thrombosis, megakaryocyte, and gene expression
Email: matthew.rondina@hsc.utah.edu
Craig Selzman, MD
Title: Professor - Surgery
The Selzman lab is focused on the transcriptional control, and in particular, the inflammatory response to myocardial injury and repair. In addition, we are exploring various forms of regenerative therapies for the damaged heart.
3i Bridge/Pillar: Cardiovascular
Keywords: heart failure, myocardial recovery, inflammation, regeneration, ischemia-reperfusion, NF-kappa B
Email: Craig.Selzman@hsc.utah.edu
Andrew Weyrich, PhD
Title: Professor - Internal Medicine (Pulmonary)
Our laboratory investigates molecular mechanisms that regulate cell/cell interactions, cell signaling, and gene expression in the inflammatory and hemostatic systems, and how these events become dysregulated in human diseases.
3i Bridge/Pillar: Cardiovascular
Keywords: inflammation, gene expression, cell signaling
Email: andy.weyrich@utah.edu
Guy Zimmerman, MD
Title: Professor - Internal Medicine (Pulmonary)
Our research group studies fundamental mechanisms of infectious, inflammatory and thrombotic diseases. These include syndromes of impaired host defense, such as the leukocyte adhesion deficiencies, and conditions in which unregulated inflammatory or thrombotic responses contribute to
3i Bridge/Pillar: Cardiovascular
Keywords: inflammation, NET, hemostasis, host responses to infection
Email: guy.zimmerman@u2m2.utah.edu