Dr. Srividya Bhaskara performed her post-doctoral research work at Vanderbilt University. Her post-doctoral work for the first time showed unconventional functions for mammalian histone deacetylases in genome stability. Her lab at HCI focuses on elucidating mechanisms by which HDACs control genome stability and normal B-cell functions such as VDJ recombination and germinal center reactions. Her lab also performs therapeutic studies for hematological cancers such as leukemia and germinal center derived diffuse large B-cell lymphoma.
3i Bridge/Pillar: Cancer
Keywords: histone deacetylases, DNA repair, immune response, cancer therapeutics and hematopoiesis, B-lymphocyte development