View all Mendoza M publications in the NIH PubMed database

Selected Publications: 

ERK Reinforces Actin Polymerization to Power Persistent Edge Protrusion during Motility.
Michelle C. Mendoza*, Marco Vilela*, Jesus E. Juarez, John Blenis, and Gaudenz Danuser (2015) Science Signaling 8:ra47 

AKT Facilitates EGFR Trafficking and Degradation by Phosphorylating and Activating PIKfyve.
E. Emrah Er, Michelle C. Mendoza, Ashley M. Mackey, Lucia E. Rameh, and John Blenis (2013) Science Signaling 6:ra34 

Phosphoregulation of the WAVE Regulatory Complex and Signal Integration.
Michelle C. Mendoza (2013) Seminars in Cell and Developmental Biology 24:272-9 

Down-regulation of CMTM8 Induces Epithelial-to-Mesenchymal-like Changes via c-MET/Extracellular Signal-Regulated Kinase (ERK) signaling. 
Wenjuan Zhang, Michelle C. Mendoza, Xiaolei Pei, Didem Ilter, Sarah J. Mahoney, Yingmei Zhang, Dalong Ma, John Blenis, and Ying Wang (2012) Journal of Biological Chemistry 287:11850-8 

Quantitative Fluorescent Speckle Microscopy (QFSM) to Measure Actin Dynamics.
Michelle C. Mendoza, Sebastien Besson, and Gaudenz Danuser (2012) Current Protocols in Cytometry 62:2.18.1-2.18.25 

ERK-MAPK Drives Lamellipodia Protrusion by Activating the WAVE2 Regulatory Complex.
Michelle C. Mendoza, E. Emrah Er*, Wenjuan Zhang*, Bryan A. Baliff, Hunter L. Elliott, Gaudenz Danuser, and John Blenis (2011) Molecular Cell 41:661-71 

The Ras-ERK and PI3K-mTOR Pathways: Cross-talk and Compensation.
Michelle C. Mendoza, E. Emrah Er, and John Blenis (2011) Trends in Biomedical Sciences 36:320-8 (2011).

ERK-MAPK Signaling in the Cytoplasm.
Michelle C. Mendoza, E. Emrah Er, and John Blenis (2010) Methods in Molecular Biology 661:185-203 

p90 Ribosomal S6 Kinase and p70 Ribosomal S6 Kinase Link Phosphorylation of the Eukaryotic Chaperonin containing TCP-1 to Growth Factor, Insulin, and Nutrient Signaling.
Yuki Abe, Sang-Oh Yoon, Kazuishi Kubota, Michelle C. Mendoza, Steven P. Gygi, and John Blenis (2009) Journal of Biological Chemistry 284:14939-48 

PHLPPing It Off: Phosphatases Get in the Akt.
Michelle C. Mendoza and John Blenis (2007) Molecular Cell 25:798-800 

MEK1 and protein phosphatase 4 coordinate Dictyostelium development and chemotaxis.
Michelle C. Mendoza, Ezgi O. Booth, Gad Shaulsky, and Richard A. Firtel (2007) Molecular and Cellular Biology 27:3817-27

PCAF modulates PTEN activity.
Koichi Okumura, Michelle Mendoza, Robert M. Bachoo, Ronald A. DePinho, Webster K. Cavenee, and Frank B. Furnari (2006) Journal of Biological Chemistry 281:26562-8 

Assaying chemotaxis of Dictyostelium cells.
Michelle C. Mendoza and Richard A. Firtel (2006) Methods in Molecular Biology 346:393-405 

Loss of SMEK, a novel, conserved protein, suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects.
Michelle C. Mendoza, Fei Du, Negin Iranfar, Nan Tang, Hui Ma, William F. Loomis, and Richard A. Firtel (2005) Molecular and Cellular Biology 25:7839-53 


Michelle Mendoza
Michelle C. Mendoza, PhD
Principle Investigator
Cancer Center Bio


The Mendoza lab has a funded collaboration with the Snyder lab to investigate the signaling mechanisms that contribute to ERK hyper-activation and tumor progression in KRas positive, Nkx2.1 negative lung cancers.  This project is jointly carried-out by Rediet Zewdu and Kelley Ingram.