CQCIT Image Analysis Core Laboratory

The CQCIT provides a standardized tumor measurement service to support imaging response assessments, which are required for primary and secondary endpoints of radiographic progression/response in interventional therapeutic clinical trials at Huntsman Cancer Institute.

Using Yunu software—formerly the Precision Imaging Metrics software and database developed by the Dana-Farber/Harvard Cancer Center Tumor Imaging Metrics Core—the CQCIT team of image analysts, research radiologists, and imaging scientists use this software to perform objective measurements with automated calculations and logic checks based on the specific response criteria. These results can be viewed through a web-based interface by the PI and study team while complete audit trails are available for regulatory compliance of GCP and 21 CFR Part 11.

The CQCIT has supported more than 16,000 imaging assessments in more than 650 cancer therapy clinical trials and 3000 patients with 106 different principal investigators, using 67 different response criteria. The CQCIT is also supporting body composition measurements using segmentation of CT scans for several investigators at Huntsman Cancer Institute.