ColoCare Study

The ColoCare Study (NCT02328677) is a prospective cohort of men and women diagnosed with primary invasive colorectal cancer (stages I-IV), with primary outcomes including quality-of-life, recurrence, and death.

It is the only colorectal cancer cohort that includes the collection of clinical and risk factor data and the sampling of a diverse panel of biospecimens at multiple critical time points (prior to surgery and at 3, 6, 12, 24, 36, 48, and 60 months post-surgery).

This unique design with repeat assessments enables innovative research into the:

  • influence of lifestyle/behavioral factors on patient outcomes;
  • ethnic/racial disparities in clinical outcomes;
  • the discovery and validation of novel biomarkers from blood, urine and stool useful for guiding treatment decision-making and risk prediction; and
  • interactions between treatment, risk factors, and biomarkers on clinical outcomes.

Dr. Ulrich initiated ColoCare together with Dr. Bill Grady at the Fred Hutchinson Cancer Research Center with subsequent consortium sites at the Moffitt Cancer Center, German Cancer Research Center, and Huntsman Cancer Institute (HCI).

ColoCare has successfully launched research on biologic determinants of:

  • colorectal cancer (e.g., tumor immunity, gut microbiome, epigenome);
  • health behaviors (e.g., physical activity, adipose tissue distribution);
  • clinical endpoints (e.g., surgical complications); as well as
  • interrelations between these factors in the context of colorectal cancer prognosis.

ColoCare Consortium Members

Other ColoCare Consortium members include currently:

In addition, ColoCare has an affiliate member at the University of Heidelberg Department of Surgery (Prof. Dr. Alexis Ulrich) and participates in several international consortia.

cornelia-ulrich.jpg
Neli Ulrich, MS, PhD
Principal Investigator
neli.ulrich@hci.utah.edu
Cancer Center Bio

Open Positions

Research Assistant Professor or Postdoctoral Research Associate. To learn more view the online posting description (PRN12645B) or view the posting ad PDF.

To learn more, view the position description to apply online or email neli.ulrich@hci.utah.edu.