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Here is a summary of some recent major scientific discoveries facilitated the Cancer Biostatistics (CB) Shared Resource.

Scientific Finding:

Sulindac plus erlotinib reduces duodenal polyps in FAP patients

Services Used:

  • Clinical trial design in P01 application
  • Interim and final analysis
  • Manuscript preparation and revision

Citation:

  • JAMA 2016, 315 (12): 1266
  • JAMA Oncol 2018 (Epub)

Scientific Finding:

Telecare increased colonoscopy uptake regardless of cost barriers

Services Used:

  • Trial design in R01 application
  • Analysis
  • Manuscript preparation

Citation:

  • Cancer Epidemiol Biomarkers Prev 2015, 24(9): 1311

Scientific Finding:

Association between socioeconomic factors and breast cancer survival differs by race

Services Used:

  • Statistical analysis
  • Manuscript preparation

Citation:

  • PLoS One 2017, 12(12) e0187018

Scientific Finding:

Breast conservation surgery associated with superior cancer-specific survival to mastectomy or mastectomy plus radiation

Services Used:

  • Statistical analysis
  • Manuscript preparation

Citation:

  • JAMA Surgery 2014,149 (3): 267

Scientific Finding:

Response to 7 days of tamoxifen is similar to longer courses in breast cancer patients

Services Used:

  • Clinical trial design
  • Analysis
  • Manuscript preparation

Citation:

  • Breast 2017, 31: 219

Scientific Finding:

Modeling the ACMG/AMP variant classification guidelines as a Bayesian classification framework.

Services Used:

  • Model development
  • Confirmation

Citation:

  • Genet. Med. 2018. Epub

Scientific Finding:

Describing the Spectrum of Patient Reported Outcomes after Radical Prostatectomy: Providing Information to Improve Patient Counseling and Shared Decision Making

Services Used:

  • Nonparametric Bayesian mixed model for distribution of functional outcomes post-prostatectomy

Citation:

  • Journal of Urology. 2018. Epub.

Scientific Finding:

Treatment of metastatic renal cell carcinoma in older patients: A network meta-analysis

Services Used:

  • Joint network meta-analysis of mRCC therapies for older patients

Citation:

  • Journal of Geriatric Oncology. 2018. Epub.

Scientific Finding:

Optimal First-Line Treatment of Metastatic Renal-Cell Carcinoma: A Network Meta-Analysis

Services Used:

  • Joint network meta-analysis of first-line mRCC therapies

Citation:

  • Kidney Cancer. 2018. 2(2):115-121.