Publications

View all Stewart RA publications in the NIH PubMed Database

Selected Publications

Spliceosomal components protect embryonic neurons from R-loop-mediated DNA damage and apoptosis.
Sorrells S, Nik S, Casey M, Cameron RC, Truong H, Toruno C, Gulfo M, Lowe A, Jette C, Stewart RA, Bowman TV (2018).
Dis Model Mech pii: dmm031583. doi: 10.1242/dmm.031583

Transplantation of Zebrafish Pediatric Brain Tumors into Immune-competent Hosts for Long-term Study of Tumor Cell Behavior and Drug Response.
Casey MJ, Modzelewska K, Anderson D, Goodman J, Boer EF, Jimenez L, Grossman D, Stewart RA (2017).
J Vis Exper 17:doi: 10.3791/55712.

Phenotypic chemical screening using a zebrafish neural crest EMT reporter identifies retinoic acid as an inhibitor of epithelial morphogenesis.
Jimenez L, Wang J, Morrison MA, Whatcott C, Soh KK, Warner S, Bearss D, Jette CA, Stewart RA (2016).
 Dis Model Mech, 9(4), 389-400

Studying the peripheral sympathetic nervous system and neuroblastoma in zebrafish.
Morrison MA, Zimmerman MW, Look AT, Stewart RA (2016).
Methods Cell Biol, 134:97-138.

MEK Inhibitors Reverse Growth of Embryonal Brain Tumors Derived from Oligoneural Precursor Cells. Modzelewska K, Boer EF, Mosbruger TL, Picard D, Anderson D, Miles RR, Kroll M, Oslund W, Pysher TJ, Schiffman JD, Jensen R, Jette CA, Huang A, Stewart RA (2016).
Cell Rep, 17:1255-1264.

Neural Crest Migration and Survival Are Susceptible to Morpholino-Induced Artifacts.
Boer EF, Jette CA, Stewart RA (2016).
PLoS One, 11(12), e0167278.

Phenotypic chemical screening using a zebrafish neural crest EMT reporter identifies retinoic acid as an inhibitor of epithelial morphogenesis.
Jimenez L, Wang J, Morrison MA, Whatcott C, Soh KK, Warner S, Bearrs D, Jette CA and Stewart RA (2016)
Dis Model Mech. 100: 127-52. (Cover and editors’ choice)

Studying peripheral sympathetic nervous system development and neuroblastoma in zebrafish.
Morrison MA, Zimmerman MW, Look AT, Stewart RA (2016).
Methods Cell Biol. 2016;134:97-138.

MEK Inhibitors Reverse Growth of Embryonal Brain Tumors Derived from Oligoneural Precursor Cells.
Modzelewska K, Boer EF, Mosbruger TL, Picard D, Anderson D, Miles RR, Kroll M, Oslund W, Pysher TJ, Schiffman JD, Jensen R, Jette CA, Huang A, Stewart RA (2016).
Cell Rep. 2016 Oct 25;17(5):1255-1264.

Neural Crest Migration and Survival Are Susceptible to Morpholino-Induced Artifacts.
Boer EF, Jette CA and Stewart RA (2016).
PLoS ONE. 11(12):e0167278. (F1000 recommended)

Fascin1-dependent Filopodia are required for directional migration of a subset of neural crest cells.
Boer EF, Howell ED, Schilling TF, Jette CA, Stewart RA (2015).
PLoS Genet, 11(1), e1004946

 

Interdependence of Bad and Puma during ionizing-radiation-induced apoptosis.
Toruno C, Carbonneau S, Stewart RA, Jette C (2014).
PLoS One. Feb 6;9(2):e88151. eCollection.

Analysis of apoptosis in zebrafish embryos by whole-mount immunofluorescence to detect activated Caspase 3.
Sorrells S, Toruno C, Stewart RA, Jette C (2013).
J Vis Exp. Dec 20;(82):e51060.

Distinct neuroblastoma-associated alterations of PHOX2B impair sympathetic neuronal differentiation in zebrafish models.
Pei D, Luther W, Wang W, Paw BH, Stewart RA, George RE (2013).
PLoS Genet. Jun;9(6):e1003533.

Future perspectives in melanoma research. Meeting report from the "Melanoma research: a bridge from Naples to the World. Napoli, December 5th-6th 2011".
Ascierto PA, Grimaldi AM, Curti B, Faries MB, Ferrone S, Flaherty K, Fox BA, Gajewski TF, Gershenwald JE, Gogas H, Grossmann K, Hauschild A, Hodi FS, Kefford R, Kirkwood JM, Leachmann S, Maio M, Marais R, Palmieri G, Morton DL, Ribas A, Stroncek DF, Stewart R, Wang E, Mozzillo N, Marincola FM (2012).
J Transl Med. Jul 4;10:83.

Activated ALK collaborates with MYCN in neuroblastoma pathogenesis.
Zhu S, Lee JS, Guo F, Shin J, Perez-Atayde AR, Kutok JL, Rodig SJ, Neuberg DS, Helman D, Feng H, Stewart RA, Wang W, George RE, Kanki JP, Look AT (2012).
Cancer Cell. Mar 20;21(3):362-73.

Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53.
Sorrells S, Carbonneau S, Harrington E, Chen AT, Hast B, Milash B, Pyati U, Major MB, Zhou Y, Zon LI, Stewart RA, Look AT, Jette C.
PLoS Genet. 2012;8(8):e1002922.

cpsf1 is required for definitive HSC survival in zebrafish.
Bolli N, Payne EM, Rhodes J, Gjini E, Johnston AB, Guo F, Lee JS, Stewart RA, Kanki JP, Chen AT, Zhou Y, Zon LI, Look AT.
Blood. 2011 Apr 14;117(15):3996-4007.

A Src-Tks5 pathway is required for neural crest cell migration during embryonic development.
Murphy DA, Diaz B, Bromann PA, Tsai JH, Kawakami Y, Maurer J, Stewart RA, Izpisúa-Belmonte JC, Courtneidge SA.
PLoS One. 2011;6(7):e22499. Erratum in: PLoS One. 2012;7(8).

Phosphatase-dependent and -independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis.
Stewart RA, Sanda T, Widlund HR, Zhu S, Swanson KD, Hurley AD, Bentires-Alj M, Fisher DE, Kontaridis MI, Look AT, Neel BG.
Dev Cell. 2010 May 18;18(5):750-62.

Studying peripheral sympathetic nervous system development and neuroblastoma in zebrafish.
Stewart RA, Lee JS, Lachnit M, Look AT, Kanki JP, Henion PD.
Methods Cell Biol. 2010;100:127-52.

BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals.
Jette CA, Flanagan AM, Ryan J, Pyati UJ, Carbonneau S, Stewart RA, Langenau DM, Look AT, Letai A.
Cell Death Differ. 2008 Jun;15(6):1063-72.

The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor.
Schlisio S, Kenchappa RS, Vredeveld LC, George RE, Stewart R, Greulich H, Shahriari K, Nguyen NV, Pigny P, Dahia PL, Pomeroy SL, Maris JM, Look AT, Meyerson M, Peeper DS, Carter BD, Kaelin WG Jr.
Genes Dev. 2008 Apr 1;22(7):884-93.

A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors.
Smolen GA, Schott BJ, Stewart RA, Diederichs S, Muir B, Provencher HL, Look AT, Sgroi DC, Peterson RT, Haber DA.
Genes Dev. 2007 Sep 1;21(17):2131-6.

The mother superior mutation ablates foxd3 activity in neural crest progenitor cells and depletes neural crest derivatives in zebrafish.
Montero-Balaguer M, Lang MR, Sachdev SW, Knappmeyer C, Stewart RA, De La Guardia A, Hatzopoulos AK, Knapik EW.
Dev Dyn. 2006 Dec;235(12):3199-212.

Zebrafish foxd3 is selectively required for neural crest specification, migration and survival.
Stewart RA, Arduini BL, Berghmans S, George RE, Kanki JP, Henion PD, Look AT.
Dev Biol. 2006 Apr 1;292(1):174-88.

Making waves in cancer research: new models in the zebrafish.
Berghmans S, Jette C, Langenau D, Hsu K, Stewart R, Look T, Kanki JP.
Biotechniques. 2005 Aug;39(2):227-37. Review.

Rodney Stewart
Rodney Stewart, PhD
Principal Investigator
rodney.stewart@hci.utah.edu
Cancer Center Bio