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The Hilgendorf Lab studies how molecular mechanisms regulate adult stem cell expansion and differentiation to ensure proper tissue homeostasis, expansion, and regeneration. A major focus of the lab is studying the molecular mechanisms regulating fat tissue, and how obesity-driven changes lead to co-morbidities, such as diabetes and cancer. We use a combination of animal models and cell culture techniques. We are very interested in how the primary cilium senses and organizes signal transduction pathways to regulate stem cell fate.

Keren Hilgendorf, PhD

Principal Investigator