Overview
The Preclinical Cancer Models Shared Resource (PCM) is a Huntsman Cancer Institute Shared Resource that supports in vivo and in vitro preclinical cancer research. PCM partners with investigators from initial study planning through experimental execution and data generation, providing scientific expertise, specialized model systems, and shared infrastructure. Its goal is to enable rigorous, efficient, and reproducible preclinical research.
Updates
Explore High-Content Imaging for Organoids, Zebrafish, and Other Preclinical Models
PCM is evaluating a demonstration Yokogawa CQ3000 high-content imaging system to support assay development and workflow optimization for live-cell and 3D imaging applications. The platform uses spinning disk confocal technology and may support future workflows involving organoids, spheroids, zebrafish models, and therapeutic screening assays. This effort aligns with PCM’s broader strategy to expand in vitro and New Approach Method capabilities (NAM) that complement established in vivo preclinical models.
Investigators interested in exploring potential applications or scheduling introductory training should contact PCM to discuss project goals, sample requirements, and current demo system availability.
Whole Animal Irradiation of Mice and Rats
The Preclinical Cancer Models (PCM) Shared Resource now offers access to the Precision X-Rad320 for whole-animal irradiation of mice and rats. The instrument is managed by PCM and housed within the HCI Research North animal facility. Supported in part by funding from the University of Utah Research Instrumentation Fund, the X-Rad320 expands access to whole-animal irradiation for University researchers. University of Utah users may obtain access by completing required radiation safety training, device-specific training with PCM staff, and animal facility access requirements. For questions about access or irradiation needs, contact PCM.
Contact Us
Email: prr@hci.utah.edu