The Microarray and Genomic Analysis Core facility provides access to the Affymetrix and Agilent Technologies microarray platforms and several Illumina Genome Analyzers (GAIIx, HiSeq2000, MiSeq, a HiSeq2500 (fall 2012)), a Caliper LabChip XT DNA sizing system, and Bravo Automated library prep robot. Together these technologies offer investigators a diverse set of tools to measure, gene, exon, or small RNA expression, SNP/CNV and DNA copy number profiling, location analysis of DNA binding proteins, DNA methylation status, and the sequencing of genomic DNA or resequencing of targeted regions of DNA.

The resource is operated as a full service facility that provides experimental handling of all aspects of the Agilent and Affymetrix microarray and of the Illumina sequencing processes. These services include evaluation of nucleic acid sample quality, labeling of samples with modified nucleotides (cy dyes or biotin), microarray hybridization, microarray scanning, feature extraction and annotation of scanned images, Illumina sequencing library preparation, exome and custom capture with Agilent SureSelect or Illumina TruSeq, and sequencing of prepared libraries on an Illumina Genome Analyzers. The Bioinformatics Core Facility provides support for additional analysis of data generated by the facility.

Contact Us

Genomics Director
Brian K. Dalley, PhD

Bioinformatic Analysis Director
David Nix, PhD


HCI Senior Director Oversight
Bradley Cairns, PhD

Faculty Advisory Committee Chair
Bradley Cairns, PhD

Faculty Advisory Committee Members
Richard Clark, PhD
Jason Gertz, PhD
Christopher Gregg, PhD
Philip Moos, PhD
Sean Tavtigian, PhD
Katherine Varley, PhD
Joseph Yost, PhD