Beckerle Lab

Studying Cell Death & Cell Division 

The Rosenblatt Lab studies both cell death and cell division and the roles that the actin and microtubule cytoskeletons play in both processes. Our lab is investigating if extrusion (a contraction that squeezes dying cells out of tissue) could drive cell death in order to control cell numbers.

Cell Life Chart

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News & Blog

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Huntsman Cancer Institute Researchers Share Expertise at National Cancer Meeting
Health Care Transformation, Clinical, Research, Education
Apr 11, 2017

Huntsman Cancer Institute Researchers Share Expertise at National Cancer Meeting

Huntsman Cancer Institute,

More than 20 researchers from Huntsman Cancer Institute (HCI) at the University of Utah made their mark on the American Association of Cancer Research (AACR) Annual Meeting this year. Held in Washington, D.C., the convention drew more than 21,500 cancer researchers from all over the world. Scientists attended sessions on topics from immunotherapy to precision medicine. About 15 researchers from HCI presented posters in the main conference hall, on a wide range of topics. ... Read More

HCI Scientist Receives $1M Award to Fund Cancer Research
Health Care Transformation, Education, Research, Clinical
Sep 22, 2016

HCI Scientist Receives $1M Award to Fund Cancer Research

Huntsman Cancer Institute,

SALT LAKE CITY—Jody Rosenblatt, Ph.D., a cell biologist at Huntsman Cancer Institute and an associate professor of oncological sciences at the University of Utah has been selected as a Howard Hughes Medical Institute (HHMI) Faculty Scholar, HHMI announced today: https://www.hhmi.org/news/philanthropies-announce-selection-faculty-scholars. The award provides $1 million to fund her research over the course of five years.... Read More

Part II: Epithelial Apoptosis: Death by Epithelial Cell Extrusion
Research
Aug 01, 2016

Part II: Epithelial Apoptosis: Death by Epithelial Cell Extrusion

Both our entire body and all of our organs are covered with a protective layer of epithelial cells. These cells are constantly replicating and dying and a balance between cell death and division is critical to maintain epithelial homeostasis. Too much cell death can lead to gaps in the epithelial barrier while excess division can result in the formation of epithelial tumors. Rosenblatt is interested in understanding the signals that regulate epithelial homeostasis. In Part 1 of her talk, Rosenblatt describes her lab’s novel finding that stretching epithelial cells causes a stretch-activated Ca2+ channel (Piezo1) to open, increasing intracellular Ca2+ levels and stimulating pathways that trigger cell division.... Read More

Part III: Pathologies Resulting From Aberrant Epithelial Extrusion
Research
Aug 01, 2016

Part III: Pathologies Resulting From Aberrant Epithelial Extrusion

Both our entire body and all of our organs are covered with a protective layer of epithelial cells. These cells are constantly replicating and dying and a balance between cell death and division is critical to maintain epithelial homeostasis. Too much cell death can lead to gaps in the epithelial barrier while excess division can result in the formation of epithelial tumors. Rosenblatt is interested in understanding the signals that regulate epithelial homeostasis. In Part 1 of her talk, Rosenblatt describes her lab’s novel finding that stretching epithelial cells causes a stretch-activated Ca2+ channel (Piezo1) to open, increasing intracellular Ca2+ levels and stimulating pathways that trigger cell division.... Read More

Part I: Epithelial Homeostasis: Cell Division
Research
Aug 01, 2016

Part I: Epithelial Homeostasis: Cell Division

Both our entire body and all of our organs are covered with a protective layer of epithelial cells. These cells are constantly replicating and dying and a balance between cell death and division is critical to maintain epithelial homeostasis.... Read More

Principle Investigator

Jody Rosenblatt, PhD
Principal Investigator
Jody.rosenblatt@hci.utah.edu

Cancer Center Bio

Contact Us

Jody Rosenblatt
H. A. and Edna Benning Presidential Endowed Chair,
HHMI Faculty Scholar,
Professor

Huntsman Cancer Institute
Department of Oncological Sciences
University of Utah
2000 Circle of Hope
Room 5342
Salt Lake City, Utah 84112
801-587-4073

Email: jody.rosenblatt@hci.utah.edu
Facebook: https://www.facebook.com/Rosenblatt-Lab-310528268965751/

Administrative Assistant:
Vanessa London
Administrative Assistant
Research Administration
Huntsman Cancer Institute
University of Utah
2000 Circle of Hope, Rm 5346
801-213-6105
Email: vanessa.london@hci.utah.edu
Phone: 801-213-4343