The Cancer Biology and Microenvironment (CBM) Program works to decipher cellular mechanisms of cancer biology through transdisciplinary research, providing a foundation for new approaches to clinical issues.

The program’s research focuses on the mechanisms by which cancer cells become transformed and/or progress to the metastatic malignant state.

CBM research is centered around the following three Specific Aims:

• To understand cellular mechanisms underlying tumor development
• To uncover mechanisms mediating tumor evolution and metastasis
• To elucidate the complex interactions among tumor cells, immune cells, and their microenvironment