The Genomics, Epigenetics, and Metabolism (GEM) Program provides innovative approaches to better understand the genetic and mechanistic basis of cancer development.

This program’s research focuses on the mechanisms underlying basic processes that go awry in cancer cells and how they contribute to oncogenesis. 

Within that broad goal, research in the GEM Program is centered in three Specific Aims: 

1. To decipher the roles of gene expression dysregulation in cancer
2. To define the causes and consequences of metabolic dysregulation in cancer
3. To understand mechanisms and consequences of genomic alterations in cancer