The Genomics, Epigenetics, and Metabolism (GEM) Program provides innovative approaches to better understand the genetic, gene regulation, and metabolic basis of cancer development and progression.

This program’s research focuses on the molecular mechanisms underlying basic processes that go awry in cancer cells and how they contribute to oncogenesis.  

Within that broad goal, research in the GEM Program is centered in three Specific Aims:  

1. To decipher the roles and mechanisms of gene expression dysregulation in cancer
2. To define the causes and consequences of metabolic dysregulation in cancer
3. To understand the mechanisms and consequences of genomic alterations in cancer