Utah Multidisciplinary Arrhythmia Collaboration (UMAC)

Utah Multidisciplinary Arrhythmia Collaboration (UMAC) Atrial fibrillation (AF) is the most common arrhythmia affecting millions of Americans and costing billions of dollars in health care costs.  Recent development in clinical cardiac electrophysiology have led to improved treatment options for patient with AF, success rates for drug therapy or interventional procedures are still far from optimal.  With this project, we are developing animal models of AF in order to study the structural and electrophysiological changes that lead to and accompany AF.  We are using state of the art MRI imaging, clinical electrical mapping, histology, and other techniques to investigate the changes in cardiac tissue as AF develops in normal, healthy hearts and becomes permanent in diseased hearts.  This revolutionary project will illuminate conditions that lead to AF, improve clinicians ability to select appropriate treatments for patients’ specific AF substrates, and aid in the development of improved AF treatment options for AF patients.