More than 20 researchers from Huntsman Cancer Institute (HCI) at the University of Utah made their mark on the American Association of Cancer Research (AACR) Annual Meeting this year. Held in Washington, D.C., the convention drew more than 21,500 cancer researchers from all over the world. Scientists attended sessions on topics from immunotherapy to precision medicine. About 15 researchers from HCI presented posters in the main conference hall, on a wide range of topics. ... Read More
Working to Understand Who Develops Cancer and Why
The Schiffman Lab studies pediatric hereditary cancer syndromes, with a special interest in genetic susceptibility to childhood cancers. Our research investigates molecular changes in childhood cancers, as well as the germline genetic variation that gives rise to childhood tumors. It is our goal to find out who gets cancer and why, so that we can develop ways to better predict, prevent, and treat cancer in the clinic.
All of our studies include the perspective of evolutionary (Darwinian) medicine, with a focus on comparative oncology to identify universal drivers of cancer risk and development. By examining the genetics of cancer in our animal relatives alongside our own, we offer a dynamic and creative approach to translational genomics. Working with collaborators from all over the country and the world, we’re able to study cancer in people, dogs, and elephants. This transdisciplinary approach continues to yield new and exciting results.
Areas of Study
- p53 and Li-Fraumeni Syndrome
- Elephant p53
- What Is Ewing Sarcoma?
- Genetic Predispositions for Ewing Sarcoma (Project GenESis)
- The Genetics of Ewing Sarcoma Tumors
Cancer in the Population
- Cancer Genetics Study
- Pediatric Biobank
News & Blog
Why elephants rarely get cancer is a mystery that has stumped scientists for decades. A study led by researchers at Huntsman Cancer Institute (HCI) at the University of Utah and Arizona State University, and including researchers from the Ringling Bros. Center for Elephant Conservation, may have found the answer.... Read More
A Worldwide Search for the Genetic Roots of Sarcoma: Utah Researchers Awarded $250,000 International Study Grant
Two physician-researchers from Huntsman Cancer Institute (HCI) at the University of Utah will be among the principal investigators (PIs) in a new worldwide study focused on the genetics of sarcoma.... Read More