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View all Mendoza M publications in the NIH PubMed database

Selected Publications:

Nascent adhesions shorten the period of lamellipodium protrusion through the Brownian ratchet mechanism
Keith R. Carney, Akib M. Khan, Samantha Stam, Shiela C. Samson, Nikhil Mittal, Sangyoon J. Han, Tamara C. Bidone, and Michelle C. Mendoza. (2023) MBoC. doi: https://doi.org/10.1091/mbc.E23-08-0314


Mechanics of lung cancer: A finite element model shows strain amplification during early tumorigenesis
Rebecca G. Zitnay, Michael Herron, Keith R. Carney, Scott Potter, Lyska L. Emerson, Jeffrey A. Weiss, and Michelle C. Mendoza. (2022) Plos Computational Biology. 18(10): e1010153.


ERK signaling for cell migration and invasion
Shiela C. Samson, Akib M. Khan, and Michelle C. Mendoza. (2022). Frontiers in Molecular Biosciences. 9:998475.


NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity
Kelley Ingram, Shiela C. Samson, Rediet Zewdu, Rebecca G. Zitnay, Eric L. Snyder, Michelle C. Mendoza. (2021) Oncogene 41: 293–300.


An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma.
Rediet Zewdu, Elnaz Mirzei Mehrabad, Kelley Ingram, Pengshu Fang, Katherine L. Gillis, Soledad A. Camolotto, Grace Orstad, Alex Jones, Michelle C. Mendoza, Benjamin T. Spike, and Eric L. Snyder (2021). Elife 10:e66788. doi: 10.7554/eLife.66788. PMID: 33821796


p90 ribosomal S6 kinase (RSK) phosphorylates myosin phosphatase and thereby controls edge dynamics during cell migration.
Shiela C. Samson, Andrew Elliott, Brian D. Mueller, Yung Kim, Keith R. Carney, Jared P. Bergman, John Blenis, and Michelle C. Mendoza (2019)
Journal of Biological Chemistry 294(28):10846-10862


AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis.
David A. Kircher, Kirby A. Trombetti, Mark R. Silvis, Gennie L. Parkman, Grant M. Fischer, Stephanie N. Angel, Christopher M. Stehn, Sean C. Strain, Allie H. Grossmann, Keith L. Duffy, Kenneth M. Boucher, Martin McMahon, Michael A. Davies, Michelle C. Mendoza, Matthew W. VanBrocklin and Sheri L. Holmen (2019)
Mol Cancer Res. MCR-18-1372.


ERK Reinforces Actin Polymerization to Power Persistent Edge Protrusion during Motility.
Michelle C. Mendoza*, Marco Vilela*, Jesus E. Juarez, John Blenis, and Gaudenz Danuser (2015) Science Signaling 8:ra47


AKT Facilitates EGFR Trafficking and Degradation by Phosphorylating and Activating PIKfyve.
E. Emrah Er, Michelle C. Mendoza, Ashley M. Mackey, Lucia E. Rameh, and John Blenis (2013) Science Signaling 6:ra34


Phosphoregulation of the WAVE Regulatory Complex and Signal Integration.
Michelle C. Mendoza (2013) Seminars in Cell and Developmental Biology 24:272-9


Down-regulation of CMTM8 Induces Epithelial-to-Mesenchymal-like Changes via c-MET/Extracellular Signal-Regulated Kinase (ERK) signaling.
Wenjuan Zhang, Michelle C. Mendoza, Xiaolei Pei, Didem Ilter, Sarah J. Mahoney, Yingmei Zhang, Dalong Ma, John Blenis, and Ying Wang (2012) Journal of Biological Chemistry 287:11850-8


Quantitative Fluorescent Speckle Microscopy (QFSM) to Measure Actin Dynamics.
Michelle C. Mendoza, Sebastien Besson, and Gaudenz Danuser (2012) Current Protocols in Cytometry 62:2.18.1-2.18.25


ERK-MAPK Drives Lamellipodia Protrusion by Activating the WAVE2 Regulatory Complex.
Michelle C. Mendoza, E. Emrah Er*, Wenjuan Zhang*, Bryan A. Baliff, Hunter L. Elliott, Gaudenz Danuser, and John Blenis (2011) Molecular Cell 41:661-71


The Ras-ERK and PI3K-mTOR Pathways: Cross-talk and Compensation.
Michelle C. Mendoza, E. Emrah Er, and John Blenis (2011) Trends in Biomedical Sciences 36:320-8 (2011).


ERK-MAPK Signaling in the Cytoplasm.
Michelle C. Mendoza, E. Emrah Er, and John Blenis (2010) Methods in Molecular Biology 661:185-203


p90 Ribosomal S6 Kinase and p70 Ribosomal S6 Kinase Link Phosphorylation of the Eukaryotic Chaperonin containing TCP-1 to Growth Factor, Insulin, and Nutrient Signaling.
Yuki Abe, Sang-Oh Yoon, Kazuishi Kubota, Michelle C. Mendoza, Steven P. Gygi, and John Blenis (2009) Journal of Biological Chemistry 284:14939-48

Michelle C. Mendoza, PhD

Principal Investigator

Collaborations

The Mendoza lab has a funded collaborations with the Weiss lab in the Biomedical Engineering department. The collaboration applies computational modeling to understand the mechanics of tumor growth within the lung.