Selected Publications

View all Evason KJ publications in NIH PubMed

Selected publications related to Liver Development and Liver Tumorigenesis

Wnt/β-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity.
So, J., Khaliq, M., Evason, K.J., Ninov, N., Martin, B.L., Stainier, D.Y.R., Shin D.
Hepatology (2017) doi:10.1002/hep.29752

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.
Farshidfar, F., Zheng, S., Gingras, M.C., Newton, Y., Shih, J., Robertson, A.G., Hinoue, T., Hoadley, K.A., Gibb, E.A., Roszik, J., Covington, K.R., Wu, C.C., Shinbrot, E., Stransky, N., Hegde, A., Yang, J.D., Reznik, E., Sadeghi, S., Pedamallu, C.S., Ojesina, A.I., Hess, J.M., Auman, J.T., Rhie, S.K., Bowlby, R., Borad, M.J.; Cancer Genome Atlas Network, Zhu, A.X., Stuart, J.M., Sander, C., Akbani, R., Cherniack, A.D., Deshpande, V., Mounajjed, T., Foo, W.C., Torbenson, M.S., Kleiner, D.E., Laird, P.W., Wheeler, D.A., McRee, A.J., Bathe, O.F., Andersen, J.B., Bardeesy, N., Roberts, L.R., Kwong, L.N. 
Cell Rep. (2017) 18:2780-2794

MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer. Anderton, B., Camarda, R., Balakrishnan, S., Balakrishnan, A., Kohnz, R.A., Lim, L., Evason, K.J., Momcilovic, O., Kruttwig, K., Huang, Q., Xu, G., Nomura, D.K., Goga, A.
EMBO Rep. (2017) 18:569-585

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth.
Cox, A.G., Hwang, K.L., Brown, K.K., Evason, K.J., Beltz, S., Tsomides, A., O'Connor, K., Galli, G.G., Yimlamai, D., Chhangawala, S., Yuan, M., Lien, E.C., Wucherpfennig, J., Nissim, S., Minami, A., Cohen, D.E., Camargo, F.D., Asara, J.M., Houvras, Y., Stainier, D.Y., Goessling, W. 
Nat Cell Biol. (2016) 18:886-96

Monocyte-dependent liver injury promotes carcinogenesis in an oncogene-specific manner.
Juric, V., Ruffell, B., Evason, K.J., Hu, J., Che, L., Wang, L., Chen, X., Bishop, J.M.
J Hepatol. (2016) pii:S0168-8278(15)00783-7

Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish.
Evason, K.J., Francisco, M.T., Juric, V., Balakrishnan, S., Lopez Pazmino, M. del P., Gordan, J.D., Kakar, S., Spitsbergen, J., Goga, A. and Stainier, D.Y.
PLoS Genet. (2015) 11:e1005305

Circulating tumor cells in hepatocellular carcinoma: a pilot study of detection, enumeration, and next-generation sequencing in cases and controls.
Kelley, R.K., Magbanua, M.J., Butler, T.M., Collisson, E.A., Hwang, J., Sidiropoulos, N., Evason, K., McWhirter, R.M., Hameed, B., Wayne, E.M., Yao, F.Y., Venook, A.P., Park, J.W.
BMC Cancer (2015) 15:206

CDK1 Inhibition Targets the p53-NOXA-MCL1 Axis, Selectively Kills Embryonic Stem Cells, and Prevents Teratoma Formation.
Huskey, N.E., Guo, T., Evason, K.J., Momcilovic, O., Pardo, D., Creasman, K.J., Judson, R.L., Blelloch, R., Oakes, S.A., Hebrok, M., Goga, A.
Stem Cell Reports (2015) 4:374-89

Cases of Spontaneous Tumor Regression in Hepatobiliary Cancers: Implications for Immunotherapy?
Parks, A.L., McWhirter, R.M., Evason, K., Kelley, R.K.
J Gastrointest Cancer (2015) 46:161-65

The perivascular niche regulates breast tumour dormancy. 
Ghajar, C.M., Peinado, H., Mori, H., Matei, I.R., Evason, K.J., Brazier, H., Almeida, D., Koller, A., Hajjar, K.A., Stainier, D.Y., Chen, E.I., Lyden, D., Bissell, M.J.
Nat Cell Biol. (2013) 15:807-17

Focal Nodular Hyperplasia and Hepatocellular Adenoma around the World Viewed through the Scope of the Immunopathological Classification. 
Balabaud, C., Al-Rabih, W.R., Chen, P.J., Evason, K., Ferrell, L., Hernandez-Prera, J.C., Huang, S.F., Longerich, T., Park, Y.N., Quaglia, A., Schirmacher, P., Sempoux, C., Thung, S.N., Torbenson, M., Wee, A., Yeh, M.M., Yeh, S.H., Le Bail, B., Zucman-Rossi, J., Bioulac-Sage, P. 
Int J Hepatol. (2013) 268625

Hepatic stellate cells in liver development, regeneration, and cancer.
*Yin, C., *Evason, K.J., Asahina, K., Stainier, D.Y.
J Clin Invest. (2013) 23:1902-10 *Equal contributions

Atypical hepatocellular adenoma-like neoplasms with β-catenin. activation show cytogenetic alterations similar to well-differentiated hepatocellular carcinomas.
Evason, K.J., 
Grenert, J.P., Ferrell, L.D., Kakar, S.
Hum Pathol. (2013) 44:750-8

The bHLH transcription factor Hand2 marks hepatic stellate cells in zebrafish: Analysis of stellate cell entry into the developing liver.
*Yin, C., *Evason, K.J., Maher, J.J., Stainier, D.Y.
Hepatology (2012) 56:1958-70 *Equal contributions

Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. 
Cheung, I.D., Bagnat, M., Ma, T.P., Datta, A., Evason, K.J., Moore, J.C., Lawson, N.D., Mostov, K.E., Moens, C.B., Stainier, D.Y.
Dev Biol. (2012) 361:68-78

Morphologic findings in progressive familial intrahepatic cholestasis 2 (PFIC2): correlation with genetic and immunohistochemical studies.
Evason, K.J., Bove, K.E., Finegold, M.J., Knisely, A.S., Rhee, S., Rosenthal, P., Miethke, A.G., Karpen, S.J., Ferrell, L.D., Kim, G.E. 
Am J Surg Pathol. (2011) 35:687-96

The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan. 
Collins, J.J., Evason, K.J., Pickett, C.L., Schneider, D.L., and Kornfeld, K.
PLoS Genetics (2008) 4:e1000230

Valproic acid extends C. elegans lifespan.
*Evason, K.J., *Collins, J.J., Huang, C., Hughes, S., and Kornfeld, K.
Aging Cell (2008) 7:305-17 *Equal contributions

Genetic and Pharmacological Factors That Influence Reproductive Aging in Nematodes.
Hughes, S.E., Evason, K.J., Xiong, C., and Kornfeld, K.
PLoS Genetics (2007) 3:e25

Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
Collins, J.J., Evason, K.J., and Kornfeld, K.
Experimental Gerontology (2006) 41:1032-9

Effects of anticonvulsant drugs on life span.
Kornfeld, K. and Evason, K.J. 
Archives of Neurology (2006) 63:491-496

Anticonvulsant medications extend C. elegans lifespan.
Evason, K.J., Huang, C., Yamben, I., Covey, D.F., and Kornfeld, K. 
Science (2005) 307:258-262

Misdirected vimentin messenger RNA alters cell morphology and motility. 
Morris, E.J., Evason, K.J., Wiand, C., L’Ecuyer, T.J., and Fulton, A.B.
Journal of Cell Science (2000) 113:2433-43

Kimberly Evason
Kimberley J. Evason, MD, PhD
Principal Investigator
kimberley.evason@hci.utah.edu
Cancer Center Bio